About Differentia
Knowledge-Empowered Modeling & Simulation for Drug Development
We combine deep scientific expertise with our AI-driven platforms to accelerate drug development and improve clinical outcomes.
Why Differentia
Modeling, Simulation, QSP & Pharmacometrics
Deep scientific expertise in mechanistic modeling and pharmacometrics, supporting disease, safety, DDI, and ADC-related mechanisms across therapeutic areas.
- Clinical trial simulation and study optimization
- Patient population simulation
- Regulatory-ready deliverables
Data Pool & AI/ML Analytics
Extensive and exclusive data resources combined with AI/ML analytics to identify valuable patterns and optimize drug development across a wide range of indications and therapeutic areas.
- Valuable pattern identification
- Drug development optimization
- Broad indication and therapeutic area coverage
Leadership
Our Core Team
Kas Subramanian
CEO
Kas, PhD, has more than 25 years of experience in applying modeling to drug discovery and development across a broad range of therapeutic areas and treatment modalities. Kas has ov...
Atefeh Kazeroonian
MECHANISTIC MODELING VP
Atefeh Kazeroonian, PhD, has over 10 years of experience in computational modeling and AI, with a focus on immunology. She successfully led international projects in Computational...
Catherine Sherwin
CLINICAL PHARMACOLOGY & PHARMACOMETRICS VP
18+ years' experience in clinical pharmacology, toxicology, pharmacometrics, and clinical trials. 15 years of experience consulting in clinical pharmacology & modeling/simulation....
Dariush Mohammadyani
VP COMMERCIAL
Dariush Mohammadyani, PhD, has over 15 years of experience in computational modeling for drug R&D. He previously served in business development leadership roles at Certara and Appl...
Rajeev Kumar
MECHANISTIC MODELING SENIOR DIRECTOR
17+ years of industry experience in mechanistic modelling supporting drug discovery and development programs and drug-induced toxicity. Led the development of a precision-based pre...
Simon Junankar
SCIENTIFIC AFFAIRS DIRECTOR
Simon Junankar, PhD, has over 20 years of research experience in oncology and immuno-oncology. His research has made important discoveries in cancer biology, cancer inflammation, c...
Scientific Advisors
Our Scientific Advisory Board
Our Scientific Advisory Board plays a pivotal role in shaping our strategic decision, ensuring that we offer our clients science-driven excellence, scientific rigor, innovation, and that we stay at the forefront of advancements.
Professor Cameron Turtle
SCIENTIFIC ADVISOR IMMUNO & CELL-THERAPY
Professor Turtle is a hemato-oncologist and physician-scientist with expertise in genetically modified T cell immunotherapies for cancer. He completed a PhD at the University of Qu...
Professor Jason Roberts
SCIENTIFIC ADVISOR PK/PD, CLINICAL PHARMACOLOGY, CLINICAL RESEARCH
Professor Jason Roberts is Director of the University of Queensland Centre for Clinical Research (UQCCR) and an Australian National Health and Medical Research Council Leadership F...
Professor Nick Holford
SCIENTIFIC ADVISOR PHARMACOMETRICS, CLINICAL PHARMACOLOGY
Professor Holford obtained his medical qualifications (MBChB, MRCP) in the United Kingdom. In 1983 he moved to Auckland, New Zealand to join the University of Auckland in the Dept...
Vision
Our Vision
At Differentia, our vision is to revolutionize drug development by harnessing the power of knowledge-empowered modeling and simulations. We are committed to improving the success rate of bringing safe and effective therapies to patients worldwide, reducing development time and costs while maintaining the highest standards of scientific rigor and innovation.
Mission
Our Mission
Our mission is to enable biopharmaceutical companies through knowledge–empowered modeling, leveraging proprietary data and AI/ML analytics for a deeper understanding of biological systems. Our services accelerate the discovery and delivery of safe and effective therapies that improve healthcare outcomes worldwide.
Our Principles
Values That Guide Us
Excellence
Science-Driven Excellence is the cornerstone of our commitment to delivering unparalleled quality and reliability in every facet of our modeling services, ensuring that our clients receive the utmost in scientific rigor and innovation.
Innovation
We are relentless innovators, driving progress, and pushing the boundaries of what's possible. We foster a culture of continuous improvement.
Continuous Learning
As a learning organization, we cultivate a culture of continuous growth, investing in the development of our employees to stay at the forefront of advancements.
Integrity
Integrity is our ethical foundation and is at the core of our business. We conduct ourselves with honesty and accountability, prioritizing data privacy and security across every level of our organization.
Customer-Focus
Working cohesively as one team, we are dedicated to our customers success, delivering tailored solutions with a customer-centric approach.